C11orf53

Across TCGA cell cohorts, C11orf53 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,042 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible C11orf53-associated GO terms across cancer lineages are Lipoxin biosynthetic process, Positive regulation of sodium ion transmembrane transport, and Positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled. Each is linked with C11orf53 in more than 4 cancer types. Because this analysis shows association rather than direction, both C11orf53-to-partner and partner-to-C11orf53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoxin biosynthetic process grouped by C11orf53-low versus C11orf53-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf53→partner) and Y-score (partner→C11orf53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Lipoxin biosynthetic process →	+1.595	+2.121	<.001	<.001	3	5
STOMACH	Positive regulation of sodium ion transmembrane transport →	+0.258	+1.226	<.001	.004	3	4
STOMACH	Positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled →	-0.107	-0.936	.002	.009	3	4
URINARY_TRACT	Wound healing involved in inflammatory response →	-0.147	-1.804	.002	.003	3	4
URINARY_TRACT	Pressure natriuresis →	+1.337	+2.386	<.001	<.001	3	4
STOMACH	Regulation of Rap protein signal transduction →	-0.783	-1.220	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,042 associations by consensus.

Lipoxin biosynthetic process by C11orf53 expression — URINARY_TRACT

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