C11orf52

Across TCGA patient cohorts, C11orf52 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,108 significant associations in total. THCA shows the largest number of these associations.

The most reproducible C11orf52-associated GO terms across cancer lineages are Peroxisome organization, Obsolete ubiquitin-dependent ERAD pathway, and Lipoprotein metabolic process. Each is linked with C11orf52 in more than 22 cancer types. Because this analysis shows association rather than direction, both C11orf52-to-partner and partner-to-C11orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peroxisome organization grouped by C11orf52-low versus C11orf52-high in UCS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf52→partner) and Y-score (partner→C11orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCS	Peroxisome organization →	+0.048	+0.298	<.001	.004	2	23
STAD	Obsolete ubiquitin-dependent ERAD pathway →	+0.052	+0.068	<.001	.001	3	20
UVM	Lipoprotein metabolic process →	+0.032	+0.133	<.001	<.001	3	20
THYM	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.048	+0.110	<.001	<.001	3	20
STAD	Intracellular protein transmembrane transport →	+0.048	+0.103	<.001	<.001	3	20
THYM	Protein localization to vacuole →	+0.052	+0.092	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,108 associations by consensus.

Peroxisome organization by C11orf52 expression — UCS

Explore this box plot interactively →