C11orf52

Across TCGA patient cohorts, C11orf52 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf52-associated genes across cancer lineages are MIR5689, MIR3134, and MIR4774. Each is linked with C11orf52 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf52-to-partner and partner-to-C11orf52 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5689 grouped by C11orf52-low versus C11orf52-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf52→partner) and Y-score (partner→C11orf52) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR5689 →	+0.512	+4.641	<.001	.006	3	1
UCEC	MIR3134 →	+0.850	+4.262	<.001	.003	3	1
UCEC	MIR4774 →	+0.525	+4.267	.003	.009	3	1
UCEC	RNU1-154P →	+0.883	+4.454	<.001	.002	3	1
BLCA	CTDSPL2P2 →	+0.029	+7.640	<.001	.009	3	1
UCEC	MIR101-2 →	+1.032	+3.943	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

MIR5689 by C11orf52 expression — UCEC

Explore this box plot interactively →