C11orf49

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, C11orf49 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C11orf49 data layer compared with 15 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher C11orf49 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated C11orf49 expression acts as an unfavorable survival marker.

OV are the cancer types where C11orf49 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVDFSMedianAll0.1650.541.00418view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

C11orf49–OV (DFS)

Kaplan–Meier survival curve for C11orf49 mutant vs wild-type samples in OV.

Open the OV breakdown →

Exploration