C11orf49

Across TCGA patient cohorts, C11orf49 mutation is significantly associated with the RNA expression of many other genes, with 214 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf49-associated genes across cancer lineages are RNU6-660P, LINC02869, and LINC02509. Each is linked with C11orf49 in more than 2 cancer types. Because this analysis shows association rather than direction, both C11orf49-to-partner and partner-to-C11orf49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-660P grouped by C11orf49-low versus C11orf49-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf49→partner) and Y-score (partner→C11orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-660P →	+0.211	+4.433	.002	.007	3	3
COAD	LINC02869 →	+0.130	+3.442	.008	.001	3	2
BLCA	LINC02509 →	+0.223	+4.704	<.001	.005	3	2
BLCA	RNY4P20 →	+0.234	+4.433	<.001	.007	3	2
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1
BRCA	ZYXP1 →	+0.248	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 214 associations by consensus.

RNU6-660P by C11orf49 expression — BLCA

Explore this box plot interactively →