C11orf45

Across TCGA patient cohorts, C11orf45 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,152 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C11orf45-associated proteins across cancer lineages are ALOX5, IL4I1, and SELPLG_S358. Each is linked with C11orf45 in more than 4 cancer types. Because this analysis shows association rather than direction, both C11orf45-to-partner and partner-to-C11orf45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C11orf45 versus ALOX5 in CCRCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf45→partner) and Y-score (partner→C11orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ALOX5 →	+0.598	+0.591	<.001	<.001	3	5
BRCA	IL4I1 →	+0.752	+0.627	<.001	<.001	3	5
OV	SELPLG_S358 →	+2.372	+0.719	.004	.002	3	4
GBM	SKAP2 →	+0.634	+0.531	<.001	<.001	3	4
CCRCC	C1S →	+0.401	+0.531	.004	.001	3	4
GBM	CASP4 →	+0.492	+0.490	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,152 associations by consensus.

C11orf45 vs ALOX5 — CCRCC

Explore this scatter interactively →