C11orf45

Across TCGA patient cohorts, C11orf45 mutation is significantly associated with the RNA expression of many other genes, with 102 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf45-associated genes across cancer lineages are MIR8071-1, C17orf98, and MIR7976. Each is linked with C11orf45 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf45-to-partner and partner-to-C11orf45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8071-1 grouped by C11orf45-low versus C11orf45-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf45→partner) and Y-score (partner→C11orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8071-1 →	+1.096	+2.285	.001	.009	3	1
UCEC	C17orf98 →	+0.660	+3.367	<.001	.008	3	1
UCEC	MIR7976 →	+0.387	+2.646	.005	.009	3	1
UCEC	MIR8071-2 →	+1.135	+2.736	.007	.007	3	1
BRCA	XKRYP1 →	+0.084	+8.471	<.001	.005	3	1
UCEC	ABHD3 →	+0.938	+3.191	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 102 associations by consensus.

MIR8071-1 by C11orf45 expression — UCEC

Explore this box plot interactively →