C11orf45

Across TCGA patient cohorts, C11orf45 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf45-associated genes across cancer lineages are CD8+ naive T-cells and Class-switched memory B-cells. Each is linked with C11orf45 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf45-to-partner and partner-to-C11orf45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by C11orf45-low versus C11orf45-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf45→partner) and Y-score (partner→C11orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.029	+2.823	.037	.036	3	1
UCEC	Class-switched memory B-cells →	-0.063	-3.321	.035	.010	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ naive T-cells by C11orf45 expression — UCEC

Explore this box plot interactively →