C11orf45

Across TCGA cell cohorts, C11orf45 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,823 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C11orf45-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Regulation of alternative mRNA splicing, via spliceosome, and RNA export from nucleus. Each is linked with C11orf45 in more than 10 cancer types. Because this analysis shows association rather than direction, both C11orf45-to-partner and partner-to-C11orf45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by C11orf45-low versus C11orf45-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf45→partner) and Y-score (partner→C11orf45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of mRNA splicing, via spliceosome →	+0.083	+1.204	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.093	+0.889	<.001	.003	3	10
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.087	+0.998	.001	.001	3	10
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.073	+0.737	<.001	.002	3	10
BREAST	Regulation of protein localization to nucleus →	+0.080	+0.944	<.001	<.001	3	9
BREAST	Regulation of G1/S transition of mitotic cell cycle →	+0.061	+0.961	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,823 associations by consensus.

Regulation of mRNA splicing, via spliceosome by C11orf45 expression — STOMACH

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