C11orf42

Across TCGA pan-cancer cohorts, C11orf42 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C11orf42 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher C11orf42 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C11orf42 expression acts as an unfavorable survival marker.

KIRC, READ, and UCEC are the cancer types where C11orf42 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.167	0.655	.038	12	view →
READ	DFS	Median	All	0.084	0.845	<.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	OS	Median	All	0.306	0.784	.002	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

C11orf42–KIRC (OS)

Open the KIRC breakdown →