C11orf42

Across TCGA patient cohorts, C11orf42 mutation is significantly associated with the RNA expression of many other genes, with 1,876 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf42-associated genes across cancer lineages are RNA5SP325, RNU6-47P, and SAR1B. Each is linked with C11orf42 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf42-to-partner and partner-to-C11orf42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP325 grouped by C11orf42-low versus C11orf42-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf42→partner) and Y-score (partner→C11orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNA5SP325 →	+0.947	+4.602	.003	.008	3	2
COAD	RNU6-47P →	+0.312	+5.122	.002	.004	3	2
UCEC	SAR1B →	+0.543	+3.609	<.001	.001	3	2
UCEC	PSMC2 →	+0.400	+3.483	.005	.002	3	2
UCEC	SMIM12 →	+0.383	+2.906	.005	.002	3	2
UCEC	ZNF367 →	+0.728	+2.906	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,876 associations by consensus.

RNA5SP325 by C11orf42 expression — COAD

Explore this box plot interactively →