C11orf42

Across TCGA cell cohorts, C11orf42 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,227 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C11orf42-associated GO terms across cancer lineages are Regulation of cilium assembly, Post-transcriptional gene silencing, and Regulation of organelle assembly. Each is linked with C11orf42 in more than 11 cancer types. Because this analysis shows association rather than direction, both C11orf42-to-partner and partner-to-C11orf42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cilium assembly grouped by C11orf42-low versus C11orf42-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf42→partner) and Y-score (partner→C11orf42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of cilium assembly →	+0.063	+0.136	.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Post-transcriptional gene silencing →	+0.087	+0.120	<.001	<.001	3	12
LARGE_INTESTINE	Regulation of organelle assembly →	+0.033	+0.277	<.001	<.001	3	11
LUNG_SCLC	Late viral transcription →	+0.119	+0.315	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA splicing, via spliceosome →	+0.138	+0.138	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA processing →	+0.133	+0.138	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,227 associations by consensus.

Regulation of cilium assembly by C11orf42 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →