C11orf40

Across TCGA pan-cancer cohorts, C11orf40 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated C11orf40 data layer compared with 14 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher C11orf40 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C11orf40 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

OV, LIHC, and LUAD are the cancer types where C11orf40 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.178	0.846	<.001	36	view →
LIHC	OS	Median	All	0.258	0.773	.018	6	view →
LUAD	DFS	Median	All	1.000	0.325	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

C11orf40–OV (OS)

Open the OV breakdown →