C11orf40

Across TCGA patient cohorts, C11orf40 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,456 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C11orf40-associated GO terms across cancer lineages are Methylation, Negative regulation of protein polyubiquitination, and Regulation of DNA binding. Each is linked with C11orf40 in more than 10 cancer types. Because this analysis shows association rather than direction, both C11orf40-to-partner and partner-to-C11orf40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by C11orf40-low versus C11orf40-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf40→partner) and Y-score (partner→C11orf40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Methylation →	+0.088	+0.224	<.001	<.001	3	11
THYM	Negative regulation of protein polyubiquitination →	+0.061	+0.051	<.001	.002	3	11
STAD	Regulation of DNA binding →	+0.083	+0.207	<.001	<.001	3	10
STAD	Positive regulation of DNA replication →	+0.085	+0.192	<.001	<.001	3	10
STAD	Nucleoside phosphate biosynthetic process →	+0.091	+0.189	<.001	<.001	3	10
STAD	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.087	+0.169	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,456 associations by consensus.

Methylation by C11orf40 expression — STAD

Explore this box plot interactively →