C11orf16

Across TCGA patient cohorts, C11orf16 mutation is significantly associated with the RNA expression of many other genes, with 694 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C11orf16-associated genes across cancer lineages are RN7SL624P, MIR8075, and LSS. Each is linked with C11orf16 in more than 1 cancer types. Because this analysis shows association rather than direction, both C11orf16-to-partner and partner-to-C11orf16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL624P grouped by C11orf16-low versus C11orf16-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf16→partner) and Y-score (partner→C11orf16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL624P →	+0.202	+4.691	<.001	<.001	3	2
UCEC	MIR8075 →	+0.949	+2.344	<.001	.002	3	2
UCEC	LSS →	+0.738	+3.329	<.001	.005	3	2
UCEC	VPS18 →	+0.645	+3.475	<.001	.002	3	2
UCEC	MAPKBP1 →	+0.673	+3.499	<.001	.002	3	2
SKCM	NUDT19P6 →	+0.040	+3.356	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 694 associations by consensus.

RN7SL624P by C11orf16 expression — BLCA

Explore this box plot interactively →