C11orf16

Across TCGA cell cohorts, C11orf16 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,035 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible C11orf16-associated GO terms across cancer lineages are mRNA export from nucleus, Regulation of translation at synapse, modulating synaptic transmission, and Telomere localization. Each is linked with C11orf16 in more than 6 cancer types. Because this analysis shows association rather than direction, both C11orf16-to-partner and partner-to-C11orf16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA export from nucleus grouped by C11orf16-low versus C11orf16-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf16→partner) and Y-score (partner→C11orf16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	mRNA export from nucleus →	+0.037	+0.047	.003	.002	3	7
BONE	Regulation of translation at synapse, modulating synaptic transmission →	+0.124	+0.061	.009	.005	3	6
URINARY_TRACT	Telomere localization →	+0.170	+0.046	<.001	.002	3	6
CNS	Nucleic acid transport →	+0.049	+0.050	<.001	.001	3	6
CNS	RNA transport →	+0.049	+0.050	<.001	.001	3	6
SOFT_TISSUE	Negative regulation of calcium ion export across plasma membrane →	+0.050	+0.048	.003	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,035 associations by consensus.

mRNA export from nucleus by C11orf16 expression — CNS

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