C11orf1

Across TCGA pan-cancer cohorts, C11orf1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated C11orf1 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C11orf1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated C11orf1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LUAD, PDAC, and HNSC are the cancer types where C11orf1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.223	0.795	.002	16	view →
PDAC	OS	Tertile	II,III,IV	0.656	0.401	.022	13	view →
HNSC	DFS	Tertile	IV	0.508	0.810	.006	12	view →
CCRCC	DFS	Tertile	IV	0.138	0.784	.024	10	view →
LSCC	DFS	Median	II,III,IV	0.485	1.000	.006	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

C11orf1–LUAD (DFS)

Open the LUAD breakdown →