C11orf1

Across TCGA patient cohorts, C11orf1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,738 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C11orf1-associated genes across cancer lineages are ZDHHC5, CHRDL1, and PTGIS. Each is linked with C11orf1 in more than 6 cancer types. Because this analysis shows association rather than direction, both C11orf1-to-partner and partner-to-C11orf1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C11orf1 versus ZDHHC5 in HNSC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C11orf1→partner) and Y-score (partner→C11orf1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZDHHC5 →	+0.528	+0.266	<.001	<.001	3	7
HNSC	CHRDL1 →	-1.428	-0.289	<.001	<.001	3	4
UCEC	PTGIS →	-1.145	-0.253	.001	<.001	3	4
HNSC	ATP8B2 →	-0.675	-0.328	<.001	.001	3	4
HNSC	PDLIM3 →	-1.593	-0.259	.001	.005	3	4
HNSC	CCL19 →	-1.277	-0.338	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,738 associations by consensus.

C11orf1 vs ZDHHC5 — HNSC

Explore this scatter interactively →