C10orf90

Across TCGA patient cohorts, C10orf90 mutation is significantly associated with the RNA expression of many other genes, with 3,859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf90-associated genes across cancer lineages are SNRPD1, RAB11FIP1P1, and PSMD9. Each is linked with C10orf90 in more than 4 cancer types. Because this analysis shows association rather than direction, both C10orf90-to-partner and partner-to-C10orf90 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPD1 grouped by C10orf90-low versus C10orf90-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf90→partner) and Y-score (partner→C10orf90) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNRPD1 →	+0.451	+2.235	.001	.006	3	5
COAD	RAB11FIP1P1 →	-0.714	-2.787	.001	.003	3	5
UCEC	PSMD9 →	+0.345	+1.852	<.001	<.001	3	5
COAD	CENPM →	+0.817	+2.710	<.001	.003	3	4
COAD	PSMA6 →	+0.590	+2.933	<.001	<.001	3	4
COAD	PFN1 →	+0.530	+2.262	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,859 associations by consensus.

SNRPD1 by C10orf90 expression — COAD

Explore this box plot interactively →