C10orf90

Across TCGA cell cohorts, C10orf90 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C10orf90-associated genes across cancer lineages are OR52E2, MS4A13, and DEFB133. Each is linked with C10orf90 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf90-to-partner and partner-to-C10orf90 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52E2 grouped by C10orf90-low versus C10orf90-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf90→partner) and Y-score (partner→C10orf90) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR52E2 →	+0.341	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	MS4A13 →	+0.207	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	DEFB133 →	+0.084	+5.228	.003	.005	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.045	+4.887	<.001	.009	3	1
LUNG_SCLC	NEU2 →	+0.015	+4.643	<.001	.004	3	1
LUNG_SCLC	ACER1 →	+0.069	+4.044	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

OR52E2 by C10orf90 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →