C10orf88

Across TCGA pan-cancer cohorts, C10orf88 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated C10orf88 data layer compared with 27 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher C10orf88 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated C10orf88 expression acts as an unfavorable survival marker.

PDAC, LUAD, and HNSC are the cancer types where C10orf88 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	II,III,IV	0.312	0.806	.007	22	view →
LUAD	OS	Median	III,IV	0.258	0.654	.040	2	view →
HNSC	OS	Median	All	0.837	1.000	.025	2	view →
LSCC	OS	Median	All	0.741	1.000	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

C10orf88–PDAC (OS)

Open the PDAC breakdown →