C10orf82

Across TCGA patient cohorts, C10orf82 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf82-associated genes across cancer lineages are N-Ras, p62 Lck ligand, and PCNA. Each is linked with C10orf82 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf82-to-partner and partner-to-C10orf82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-Ras grouped by C10orf82-low versus C10orf82-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf82→partner) and Y-score (partner→C10orf82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	N-Ras →	-0.137	-3.308	.028	.010	3	1
UCEC	p62 Lck ligand →	+0.496	+3.009	.003	.019	3	1
UCEC	PCNA →	+0.235	+3.321	.037	.010	2	2
UCEC	Annexin-1 →	+0.727	+2.827	.008	.035	3	1
UCEC	SCD →	-0.147	-2.986	.011	.035	3	1
UCEC	Smad4 →	-0.170	-2.999	.007	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

N-Ras by C10orf82 expression — UCEC

Explore this box plot interactively →