C10orf82

Across TCGA cell cohorts, C10orf82 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C10orf82-associated genes across cancer lineages are P2RY12, KLF18, and CD300H. Each is linked with C10orf82 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf82-to-partner and partner-to-C10orf82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, P2RY12 grouped by C10orf82-low versus C10orf82-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf82→partner) and Y-score (partner→C10orf82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	P2RY12 →	+0.236	+4.273	<.001	.006	3	1
LARGE_INTESTINE	KLF18 →	+0.012	+4.930	<.001	.001	3	1
LARGE_INTESTINE	CD300H →	+0.039	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

P2RY12 by C10orf82 expression — LARGE_INTESTINE

Explore this box plot interactively →