C10orf71-AS1

Across TCGA pan-cancer cohorts, C10orf71-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of C10orf71-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where C10orf71-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types C10orf71-AS1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and HNSC are the cancer types where C10orf71-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C10orf71-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	−0.340	<.001	12	view →
KIRP	All	III,IV	−0.369	<.001	11	view →
HNSC	Male	All	−1.142	.001	8	view →
LUAD	All	All	+0.161	.004	2	view →
PRAD	All	All	−0.142	.042	2	view →
LUSC	Female	III,IV	−0.105	.002	1	view →
LIHC	Female	All	+0.072	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

C10orf71-AS1–KIRC

Open the KIRC breakdown →