C10orf67

Across TCGA patient cohorts, C10orf67 mutation is significantly associated with the RNA expression of many other genes, with 142 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf67-associated genes across cancer lineages are NPB, CIDECP1, and XRCC2. Each is linked with C10orf67 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf67-to-partner and partner-to-C10orf67 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPB grouped by C10orf67-low versus C10orf67-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf67→partner) and Y-score (partner→C10orf67) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NPB →	+0.097	+3.305	<.001	.001	3	1
UCEC	CIDECP1 →	+0.581	+3.223	<.001	.009	3	1
UCEC	XRCC2 →	+0.921	+3.223	<.001	.009	3	1
UCEC	RNU1-17P →	+0.389	+3.935	<.001	<.001	3	1
UCEC	RNA5SP379 →	+0.801	+3.452	<.001	<.001	3	1
UCEC	LIN52 →	+0.569	+3.202	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 142 associations by consensus.

NPB by C10orf67 expression — UCEC

Explore this box plot interactively →