C10orf67

Across TCGA cell cohorts, C10orf67 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C10orf67-associated genes across cancer lineages are ADRA1A, PRAMEF20, and OPN1MW3. Each is linked with C10orf67 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf67-to-partner and partner-to-C10orf67 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADRA1A grouped by C10orf67-low versus C10orf67-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf67→partner) and Y-score (partner→C10orf67) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ADRA1A →	+0.216	+4.273	<.001	.006	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	OPN1MW3 →	+0.004	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ADRA1A by C10orf67 expression — LARGE_INTESTINE

Explore this box plot interactively →