Across TCGA patient cohorts, C10orf62 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C10orf62-associated genes across cancer lineages are INPP4B, MEK1, and mTOR_pS2448. Each is linked with C10orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf62-to-partner and partner-to-C10orf62 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf62→partner) and Y-score (partner→C10orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.502	-3.459	.001	.005	3	1
UCEC	MEK1 →	+0.446	+2.459	.011	.020	3	1
UCEC	mTOR_pS2448 →	-0.184	-2.459	.010	.020	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.560	-2.446	.009	.020	3	1
UCEC	Paxillin →	+0.267	+3.179	.032	.010	3	1
UCEC	PDCD4 →	-0.654	-2.459	.003	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

C10orf62 survival (RNA) · tumor vs normal (RNA) · all C10orf62 data types