C10orf53

Across TCGA patient cohorts, C10orf53 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,759 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C10orf53-associated GO terms across cancer lineages are Microtubule-based transport, Nucleotide-excision repair, and Regulation of microtubule-based process. Each is linked with C10orf53 in more than 13 cancer types. Because this analysis shows association rather than direction, both C10orf53-to-partner and partner-to-C10orf53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by C10orf53-low versus C10orf53-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf53→partner) and Y-score (partner→C10orf53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Microtubule-based transport →	+0.038	+0.048	<.001	<.001	3	14
STAD	Nucleotide-excision repair →	+0.047	+0.054	<.001	<.001	3	13
STAD	Regulation of microtubule-based process →	+0.044	+0.061	<.001	<.001	3	13
ESCA	Telomerase RNA localization →	+0.081	+0.102	<.001	.003	2	13
STAD	Protein stabilization →	+0.055	+0.055	<.001	<.001	3	12
STAD	Intracellular protein transmembrane transport →	+0.052	+0.055	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,759 associations by consensus.

Microtubule-based transport by C10orf53 expression — STAD

Explore this box plot interactively →