C10orf53

Across TCGA cell cohorts, C10orf53 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,022 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C10orf53-associated GO terms across cancer lineages are Acrosome assembly, Purine deoxyribonucleoside triphosphate catabolic process, and Cell communication by electrical coupling. Each is linked with C10orf53 in more than 3 cancer types. Because this analysis shows association rather than direction, both C10orf53-to-partner and partner-to-C10orf53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acrosome assembly grouped by C10orf53-low versus C10orf53-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf53→partner) and Y-score (partner→C10orf53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Acrosome assembly →	-0.079	-0.020	.001	.004	3	4
BONE	Purine deoxyribonucleoside triphosphate catabolic process →	-0.105	-0.435	.001	<.001	3	3
BONE	Cell communication by electrical coupling →	-0.167	-0.330	<.001	<.001	3	3
BONE	Negative regulation of angiogenesis →	-0.142	-0.280	<.001	.004	3	3
BONE	Peptidyl-lysine oxidation →	-1.559	-0.337	<.001	<.001	3	3
BONE	Protein oxidation →	-1.638	-0.337	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,022 associations by consensus.

Acrosome assembly by C10orf53 expression — BLOOD_Myeloma

Explore this box plot interactively →