Across TCGA patient cohorts, C10orf105 protein abundance is significantly associated with the RNA expression of many other genes, with 228 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C10orf105-associated genes across cancer lineages are MID1, MAPK3, and CDH23. Each is linked with C10orf105 in more than 1 cancer types. Because this analysis shows association rather than direction, both C10orf105-to-partner and partner-to-C10orf105 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C10orf105→partner) and Y-score (partner→C10orf105) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MID1 →	-1.173	-1.259	<.001	.001	3	1
GBM	MAPK3 →	+0.445	+1.275	.003	.006	3	1
GBM	CDH23 →	+0.823	+0.997	.006	<.001	3	1
GBM	DAO →	+0.655	+1.452	<.001	<.001	3	1
GBM	MTRF1L →	-0.446	-1.097	.002	<.001	3	1
GBM	MRPL18 →	-0.337	-0.821	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 228 associations by consensus.

Exploration

C10orf105 survival (RNA) · tumor vs normal (RNA) · all C10orf105 data types