BZW1P2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, BZW1P2 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of BZW1P2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where BZW1P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BZW1P2 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

COAD, KICH, and BRCA are the cancer types where BZW1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BZW1P2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADAllII,III,IV+0.638<.0019view →
KICHAllII,III,IV−0.619<.0018view →
BRCAAllII,III,IV+0.405<.0018view →
LUADAllAll+0.780<.0016view →
UCECAllII,III,IV+0.694.0364view →
LUSCMaleAll+0.427<.0014view →
READAllIII,IV+0.740.0262view →
STADAllII,III,IV+0.498.0301view →
KIRCMaleIII,IV−0.229.0381view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

Exploration