BZW1P1

Across TCGA pan-cancer cohorts, BZW1P1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of BZW1P1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where BZW1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BZW1P1 is over-expressed in tumor, although a few such as LIHC and READ show the opposite, repressed pattern.

HNSC, BRCA, and COAD are the cancer types where BZW1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BZW1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.111	<.001	7	view →
BRCA	All	All	+0.070	<.001	6	view →
COAD	All	All	+0.207	<.001	5	view →
LUSC	Male	II,III,IV	+0.104	.003	4	view →
LUAD	All	All	+0.102	<.001	4	view →
LIHC	Female	II,III,IV	−0.031	.019	2	view →
READ	All	All	−0.071	.038	1	view →
KIRC	All	IV	−0.049	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

BZW1P1–HNSC

Open the HNSC breakdown →