BZW1

Across TCGA pan-cancer cohorts, BZW1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BZW1 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher BZW1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated BZW1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

PDAC, UCEC, and HNSC are the cancer types where BZW1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.672	0.852	.001	80	view →
UCEC	OS	Median	All	0.983	0.843	.007	52	view →
HNSC	DFS	Tertile	All	0.903	0.665	.002	42	view →
LUAD	DFS	Median	All	0.481	0.798	<.001	28	view →
CCRCC	OS	Quartile	All	0.717	0.953	.012	25	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BZW1–PDAC (DFS)

Open the PDAC breakdown →