BZW1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BZW1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,354 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BZW1-associated genes across cancer lineages are COLCA1, HLF, and NCAPH. Each is linked with BZW1 in more than 6 cancer types. Because this analysis shows association rather than direction, both BZW1-to-partner and partner-to-BZW1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BZW1 versus COLCA1 in LSCC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BZW1→partner) and Y-score (partner→BZW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCOLCA1 →-1.395-0.225<.001.00137
HNSCHLF →-0.977-0.299<.001<.00136
OVNCAPH →+0.756+0.228.001.00836
GBMNDRG2 →-1.030-0.245.001<.00136
OVE2F3 →+0.597+0.311<.001<.00135
PDACHJURP →+0.905+0.422<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,354 associations by consensus.

BZW1 vs COLCA1 — LSCC

Per-sample scatter of BZW1 vs COLCA1 in LSCC (Pearson r = -0.31).

Explore this scatter interactively →

Exploration