BZW1-AS1

Across TCGA pan-cancer cohorts, BZW1-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of BZW1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where BZW1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BZW1-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

BRCA, COAD, and KICH are the cancer types where BZW1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BZW1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	+0.118	.004	6	view →
COAD	All	II,III,IV	+0.296	<.001	5	view →
KICH	All	All	−0.075	<.001	4	view →
KIRP	All	III,IV	+0.107	.023	3	view →
LUAD	Female	II,III,IV	+0.107	.017	2	view →
STAD	All	All	+0.074	.043	1	view →
LUSC	All	All	+0.056	.048	1	view →
THCA	All	All	−0.032	.037	1	view →
KIRC	Male	II,III,IV	+0.027	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

BZW1-AS1–BRCA

Open the BRCA breakdown →