BYSL

Across TCGA cell cohorts, BYSL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,726 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BYSL-associated GO terms across cancer lineages are Maturation of SSU-rRNA, rRNA processing, and rRNA 5'-end processing. Each is linked with BYSL in more than 18 cancer types. Because this analysis shows association rather than direction, both BYSL-to-partner and partner-to-BYSL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by BYSL-low versus BYSL-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BYSL→partner) and Y-score (partner→BYSL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Maturation of SSU-rRNA →	+0.132	+1.212	<.001	<.001	3	19
BONE	rRNA processing →	+0.122	+0.841	.001	.002	3	19
LUNG_NSCLC_LUSC	rRNA 5'-end processing →	+0.170	+1.092	<.001	.008	3	18
BONE	rRNA metabolic process →	+0.153	+1.086	<.001	.001	3	18
URINARY_TRACT	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.157	+0.953	<.001	<.001	3	18
BONE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.142	+1.006	<.001	.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,726 associations by consensus.

Maturation of SSU-rRNA by BYSL expression — PANCREAS

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