BUD23

Across TCGA cell cohorts, BUD23 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,922 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BUD23-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgG isotypes, Pre-mRNA catabolic process, and Ribonucleoside triphosphate biosynthetic process. Each is linked with BUD23 in more than 13 cancer types. Because this analysis shows association rather than direction, both BUD23-to-partner and partner-to-BUD23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of isotype switching to IgG isotypes grouped by BUD23-low versus BUD23-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BUD23→partner) and Y-score (partner→BUD23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of isotype switching to IgG isotypes →	+0.139	+0.744	<.001	.001	3	14
BONE	Pre-mRNA catabolic process →	+0.183	+0.487	<.001	.007	3	13
BONE	Ribonucleoside triphosphate biosynthetic process →	+0.121	+0.708	<.001	<.001	3	12
BONE	Mitochondrial large ribosomal subunit assembly →	+0.125	+0.808	<.001	.001	3	12
BONE	Protein-DNA complex disassembly →	+0.132	+0.602	.007	.007	3	12
UPPER_AERODIGESTIVE_TRACT	Peptidyl-glutamic acid carboxylation →	+0.109	+0.868	<.001	.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,922 associations by consensus.

Positive regulation of isotype switching to IgG isotypes by BUD23 expression — BONE

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