BUD13

Across TCGA patient cohorts, BUD13 mutation is significantly associated with the RNA expression of many other genes, with 3,042 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BUD13-associated genes across cancer lineages are RN7SL62P, PIGW, and NCAPD3. Each is linked with BUD13 in more than 2 cancer types. Because this analysis shows association rather than direction, both BUD13-to-partner and partner-to-BUD13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL62P grouped by BUD13-low versus BUD13-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BUD13→partner) and Y-score (partner→BUD13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL62P →	+0.132	+4.812	<.001	.006	3	3
UCEC	PIGW →	+0.489	+2.747	.006	<.001	3	3
UCEC	NCAPD3 →	+0.571	+1.858	.002	.005	3	3
SKCM	EIF5B →	+0.652	+3.591	.005	.001	3	3
UCEC	AP3D1 →	+0.524	+2.732	<.001	.003	3	3
SKCM	PMS2P4 →	+0.522	+3.591	.005	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,042 associations by consensus.

RN7SL62P by BUD13 expression — CESC

Explore this box plot interactively →