BUB3

Across TCGA patient cohorts, BUB3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,847 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BUB3-associated genes across cancer lineages are NUP85, CEP95, and TADA2A. Each is linked with BUB3 in more than 7 cancer types. Because this analysis shows association rather than direction, both BUB3-to-partner and partner-to-BUB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BUB3 versus NUP85 in HNSC, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BUB3→partner) and Y-score (partner→BUB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NUP85 →	+0.552	+0.188	.009	.001	3	8
HNSC	CEP95 →	+0.572	+0.218	<.001	<.001	3	8
LSCC	TADA2A →	+0.678	+0.254	<.001	<.001	3	8
LSCC	MYO19 →	+0.703	+0.258	<.001	<.001	3	8
LSCC	NLE1 →	+0.866	+0.277	<.001	<.001	3	8
LSCC	SPAG5 →	+1.081	+0.321	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,847 associations by consensus.

BUB3 vs NUP85 — HNSC

Explore this scatter interactively →