BUB1

Across TCGA patient cohorts, BUB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 27,572 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BUB1-associated proteins across cancer lineages are RIF1, RPL12_S38, and RRM1. Each is linked with BUB1 in more than 9 cancer types. Because this analysis shows association rather than direction, both BUB1-to-partner and partner-to-BUB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BUB1 versus RIF1 in LSCC, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BUB1→partner) and Y-score (partner→BUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIF1 →	+0.563	+0.944	<.001	<.001	3	10
LUAD	RPL12_S38 →	+1.397	+1.332	<.001	<.001	3	10
COAD	RRM1 →	+0.523	+0.677	<.001	<.001	3	10
LUAD	RRM2 →	+0.978	+1.347	<.001	<.001	3	10
LSCC	RRP36_S73 →	+1.049	+0.889	<.001	<.001	3	10
GBM	SMC2 →	+0.834	+1.241	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,572 associations by consensus.

BUB1 vs RIF1 — LSCC

Explore this scatter interactively →