BUB1

Across TCGA patient cohorts, BUB1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,370 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BUB1-associated genes across cancer lineages are GINS1, FOXM1, and TTK. Each is linked with BUB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BUB1-to-partner and partner-to-BUB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BUB1 versus GINS1 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BUB1→partner) and Y-score (partner→BUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS1 →	+1.310	+0.603	<.001	.001	3	5
UCEC	FOXM1 →	+1.205	+0.500	.002	.003	3	5
UCEC	TTK →	+1.373	+0.668	.002	<.001	3	5
UCEC	CENPF →	+1.296	+0.492	.002	<.001	3	5
UCEC	KIF14 →	+1.213	+0.508	.001	.002	3	5
GBM	NCAPH →	+0.850	+0.542	.003	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,370 associations by consensus.

BUB1 vs GINS1 — UCEC

Explore this scatter interactively →