BTRC

Across TCGA patient cohorts, BTRC RNA expression is significantly associated with the protein abundance of many other proteins, with 20,208 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BTRC-associated proteins across cancer lineages are PLEKHA1, P4HB, and CACUL1. Each is linked with BTRC in more than 5 cancer types. Because this analysis shows association rather than direction, both BTRC-to-partner and partner-to-BTRC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTRC versus PLEKHA1 in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BTRC→partner) and Y-score (partner→BTRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHA1 →	+0.719	+0.434	<.001	<.001	3	6
GBM	P4HB →	-0.527	-0.507	<.001	<.001	3	6
BRCA	CACUL1 →	+0.217	+0.497	<.001	.001	3	5
PDAC	CTBP2 →	+0.389	+0.305	<.001	<.001	3	5
PDAC	DCTN3 →	+0.334	+0.292	<.001	.001	3	5
UCEC	SLK →	+0.384	+0.424	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,208 associations by consensus.

BTRC vs PLEKHA1 — LSCC

Explore this scatter interactively →