BTRC

Across TCGA patient cohorts, BTRC protein abundance is significantly associated with the protein abundance of many other proteins, with 2,022 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BTRC-associated proteins across cancer lineages are WASHC2A_S1087, R3HCC1L, and KIFC3. Each is linked with BTRC in more than 2 cancer types. Because this analysis shows association rather than direction, both BTRC-to-partner and partner-to-BTRC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BTRC versus WASHC2A_S1087 in BRCA, with a Pearson correlation of -0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BTRC→partner) and Y-score (partner→BTRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WASHC2A_S1087 →	-1.494	-0.701	<.001	<.001	3	2
BRCA	R3HCC1L →	+0.430	+0.522	<.001	<.001	3	2
LUAD	KIFC3 →	+0.431	+0.649	.001	<.001	3	2
BRCA	ARF1 →	-0.896	-0.810	.001	<.001	3	1
GBM	SV2B_S25 →	+1.965	+0.447	<.001	<.001	3	1
GBM	TESPA1 →	+0.759	+0.558	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,022 associations by consensus.

BTRC vs WASHC2A_S1087 — BRCA

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