BTRC

Across TCGA cell cohorts, BTRC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,281 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BTRC-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Regulation of sister chromatid cohesion, and Negative regulation of smoothened signaling pathway. Each is linked with BTRC in more than 14 cancer types. Because this analysis shows association rather than direction, both BTRC-to-partner and partner-to-BTRC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by BTRC-low versus BTRC-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BTRC→partner) and Y-score (partner→BTRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Viral translational termination-reinitiation →	+0.092	+0.700	.002	.003	3	15
BLOOD_Myeloma	Regulation of sister chromatid cohesion →	+0.143	+0.966	<.001	.001	3	15
STOMACH	Negative regulation of smoothened signaling pathway →	+0.077	+0.752	.002	.001	3	14
LUNG_NSCLC_LUSC	Regulation of smoothened signaling pathway →	+0.044	+0.530	.006	.008	3	14
LUNG_SCLC	Protein localization to ciliary membrane →	+0.100	+0.608	<.001	<.001	3	14
LUNG_SCLC	Regulation of maintenance of sister chromatid cohesion →	+0.131	+0.585	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,281 associations by consensus.

Viral translational termination-reinitiation by BTRC expression — BONE

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