BTNL9

Across TCGA patient cohorts, BTNL9 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTNL9-associated genes across cancer lineages are PDCD4, TAZ, and Bap1-c-4. Each is linked with BTNL9 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTNL9-to-partner and partner-to-BTNL9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by BTNL9-low versus BTNL9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTNL9→partner) and Y-score (partner→BTNL9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.862	-3.459	<.001	.005	3	2
COAD	TAZ →	+0.313	+2.832	.002	.034	3	2
COAD	Bap1-c-4 →	-0.469	-2.991	.001	.036	3	2
UCEC	STAT3_pY705 →	-0.529	-3.169	<.001	.018	3	2
COAD	Lck →	+0.311	+3.025	.049	.019	2	2
COAD	Mre11 →	+0.147	+2.820	.016	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

PDCD4 by BTNL9 expression — UCEC

Explore this box plot interactively →