BTNL3

Across TCGA cell cohorts, BTNL3 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BTNL3-associated genes across cancer lineages are PRSS58, ZNF831, and TAFA1. Each is linked with BTNL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTNL3-to-partner and partner-to-BTNL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS58 grouped by BTNL3-low versus BTNL3-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTNL3→partner) and Y-score (partner→BTNL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRSS58 →	+0.092	+5.000	<.001	.006	3	1
LARGE_INTESTINE	ZNF831 →	+0.018	+4.273	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.410	+4.273	<.001	.006	3	1
LARGE_INTESTINE	BPIFA1 →	+0.191	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.227	+4.095	<.001	.009	3	1
LUNG_SCLC	IFNA16 →	+0.282	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PRSS58 by BTNL3 expression — PANCREAS

Explore this box plot interactively →