Across TCGA patient cohorts, BTNL2 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTNL2-associated genes across cancer lineages are 4E-BP1, PCNA, and Src_pY527. Each is linked with BTNL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTNL2-to-partner and partner-to-BTNL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTNL2→partner) and Y-score (partner→BTNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.504	+3.199	<.001	.009	3	2
UCEC	PCNA →	+0.299	+3.321	.008	.010	3	1
UCEC	Src_pY527 →	-0.564	-2.990	.012	.036	3	1
UCEC	STAT3_pY705 →	-0.480	-3.321	<.001	.010	3	1
UCEC	BRD4 →	+0.299	+2.177	.033	.035	3	1
UCEC	Cyclin-B1 →	+0.891	+3.000	.002	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

BTNL2 survival (RNA) · tumor vs normal (RNA) · all BTNL2 data types