BTN3A3

Across TCGA patient cohorts, BTN3A3 mutation is significantly associated with the RNA expression of many other genes, with 2,098 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTN3A3-associated genes across cancer lineages are S100A15A, OR5AC4P, and RNU6-1311P. Each is linked with BTN3A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTN3A3-to-partner and partner-to-BTN3A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S100A15A grouped by BTN3A3-low versus BTN3A3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN3A3→partner) and Y-score (partner→BTN3A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	S100A15A →	+0.963	+3.678	<.001	.009	3	2
BRCA	OR5AC4P →	+0.160	+4.231	<.001	.003	3	2
HNSC	RNU6-1311P →	+0.259	+4.015	.006	.003	3	2
SKCM	UQCRFS1P2 →	+0.062	+3.490	<.001	.008	3	2
COAD	BCAR1P2 →	+0.145	+5.173	<.001	.001	3	2
UCEC	SMIM15P2 →	+0.472	+1.797	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,098 associations by consensus.

S100A15A by BTN3A3 expression — BRCA

Explore this box plot interactively →