Across TCGA pan-cancer cohorts, BTN3A2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated BTN3A2 data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher BTN3A2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BTN3A2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where BTN3A2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	1.000	0.539	.013	13	view →
HNSC	DFS	Tertile	All	0.624	0.953	.013	11	view →
LUAD	DFS	Tertile	II,III,IV	0.677	0.247	.039	2	view →
LSCC	OS	Tertile	All	0.953	0.831	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: BTN3A2 tumor-vs-normal RNA expression · all BTN3A2 data types