Across TCGA patient cohorts, BTN3A2 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BTN3A2-associated genes across cancer lineages are ACC1, 4E-BP1, and C-Raf. Each is linked with BTN3A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BTN3A2-to-partner and partner-to-BTN3A2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BTN3A2→partner) and Y-score (partner→BTN3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.329	+1.736	.009	.007	3	2
UCEC	4E-BP1 →	+0.436	+3.906	<.001	<.001	3	2
UCEC	C-Raf →	+0.216	+2.070	<.001	.001	3	2
UCEC	EGFR_pY1068 →	-0.245	-2.700	.004	.005	3	1
UCEC	eIF4E →	+0.172	+2.070	.018	.001	3	1
UCEC	FASN →	+0.362	+2.000	.008	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

BTN3A2 survival (RNA) · tumor vs normal (RNA) · all BTN3A2 data types